Lecture 'Molecular basis of cell death-driven inflammation'

For whom
Business , Employees , Students
10-06-2022 from 11:30 to 12:30
UGent-VIB-onderzoeksgebouw, Technologiepark 71, 9052 Zwijnaarde
VIB-UGent Center for Inflammation Research

Petr Broz (University of Lausanne) will share new insights on how different forms of cell death are sensed and what molecules are released.

Programmed cell death (PCD) controls the elimination of unnecessary, damaged, malignant, or infected cells during development and tissue homeostasis. Apoptosis—the best-studied form of PCD—leads to the disintegration of dying cells into apoptotic bodies that maintain membrane integrity and are removed by phagocytes in an immunologically silent manner. In contrast to apoptosis, programmed necrotic cell death, such as pyroptosis and necroptosis, results in cell lysis, which drives inflammation and immune responses. While the molecular basis of cell death signaling has been explored, very little is still known about how different forms of PCD are sensed, and what molecules are released by different forms of PCD. Here we will discuss new insights into this questions, as well as the molecular drivers of cell lysis.

Registration for this presentation is not required. Online attending is also possible.