Quetelet seminar by Prof. Vansteelandt and dr. Dukes

21-06-2021 from 16:00 to 17:00
digital (zoom)
Jan De Neve

The seminar will give a gentle and broadly accessible introduction to the paper (the so-called "the introductory pre-meeting (DeMO) of an RSS read paper") and discuss implications for modern statistics education.


Inference for the parameters indexing generalised linear models is routinely based on the assumption that the model is correct and a priori specified. This is unsatisfactory because the chosen model is usually the result of a data-adaptive model selection process, which may induce excess uncertainty that is not usually acknowledged. Moreover, the assumptions encoded in the chosen model rarely represent some a priori known, ground truth, making standard inferences prone to bias, but also failing to give a pure reflection of the information that is contained in the data. Inspired by developments on assumption-free inference for so-called projection parameters, we here propose novel nonparametric definitions of main effect estimands and effect modification estimands. These reduce to standard main effect and effect modification parameters in generalised linear models when these models are correctly specified, but have the advantage that they continue to capture respectively the primary (conditional) association between two variables, or the degree to which two variables interact (in a statistical sense) in their effect on outcome, even when these models are misspecified. We achieve an assumption-lean inference for these estimands (and thus for the underlying regression parameters) by deriving their influence curve under the nonparametric model and invoking flexible data-adaptive (e.g., machine learning) procedures.



Meeting ID: 996 0279 8361
Passcode: DjXc8rbX